Jeremy Ward will start at inside centre for the Sharks against the Jaguares in Buenos Aires on Saturday.
Ward replaces André Esterhuizen, who received a six-week suspension for a dangerous tackle against the Rebels last weekend.
In other changes to the backline, Odwa Ndungane starts on the right wing and Michael Claassens rotates with Cobus Reinach at scrumhalf.
Up front, there is a new front row in Thomas du Toit, Chiliboy Ralepelle and Lourens Adriaanse.
Ruan Botha replaces Etienne Oosthuizen at No 4 lock, while Jean-Luc du Preez starts at openside flank ahead of regular skipper Tera Mtembu, who drops to the bench.
Philip van der Walt will captain the side.
Sharks – 15 Rhyno Smith, 14 Odwa Ndungane, 13 Lukhanyo Am, 12 Jeremy Ward, 11 Lwazi Mvovo, 10 Curwin Bosch, 9 Michael Claassens, 8 Daniel du Preez, 7 Jean-Luc du Preez, 6 Philip van der Walt (c), 5 Stephan Lewies, 4 Ruan Botha, 3 Lourens Adriaanse, 2 Chiliboy Ralepelle, 1 Thomas du Toit
Subs: 16 Franco Marais, 17 Juan Schoeman, 18 Coenie Oosthuizen, 19 Etienne Oosthuizen, 20 Tera Mtembu, 21 Cobus Reinach, 22 Benhard Janse van Rensburg, 23 Johan Deysel.
Photo: Steve Haag/Gallo Images