England flank Chris Robshaw will undergo surgery on his left shoulder on Monday that will sideline him for 12 weeks.
Robshaw suffered the injury while playing for Harlequins against Worcester on 1 January.
England coach Eddie Jones hinted that lock Maro Itoje could replace Robshaw at blindside for the Six Nations.
'Maro at six is something we will definitely look at,' said Jones. 'He has a pretty good engine on him, is reasonably athletic and is a good one-on-one tackler, which is essential at No 6.'
England have already lost Billy and Mako Vunipola for the opening game of the Six Nations against France through injury.
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