Reece Hodge will start on the wing in one of two changes to the Wallabies' side to face the Boks in Brisbane this Saturday.
Hodge will earn his first start for the Wallabies after impressing off the bench in the last match against the All Blacks in Wellington two weeks ago, and will take over in the absence of veteran Adam Ashley-Cooper, who has returned to French club Bordeaux.
In the only other change, Dean Mumm will start at blindside flank in his 49th Test, and David Pocock and Michael Hooper in the back row.
Coach Michael Cheika has named an extended bench with one to be omitted following the final training run at Ballymore Stadium on Friday.