England head coach Eddie Jones has made eight changes to the starting lineup for the Six Nations match against Italy in Rome on Sunday.
There are three changes to the backline as utility back Elliot Daly and scrumhalf Ben Youngs both drop to the bench.
Joe Marchant shifts from the wing to outside centre, while Jack Nowell is promoted from the bench to start on the left wing.
Bristol Bears scrumhalf Harry Randall, 24, replaces Youngs in a halfback partnership with Marcus Smith.
A new-look pack sees Alex Dombrandt take Sam Simmonds’ place at No 8, while Maro Itoje moves from lock to blindside flank. Charlie Ewels starts at lock, while Will Stuart and Jamie George rotate with Kyle Sinckler and Luke Cowan-Dickie in the front row.
Youngs will on Sunday become the joint most-capped England player of all time, alongside Jason Leonard, if he plays off the bench. Youngs made his debut against Scotland in March 2010 and is in line to add to his 113 caps.
Ollie Chessum will be eager to make his England debut this weekend after being named on the bench.
England – 15 Freddie Steward, 14 Max Malins, 13 Joe Marchant, 12 Henry Slade, 11 Jack Nowell, 10 Marcus Smith, 9 Harry Randall, 8 Alex Dombrandt, 7 Tom Curry (c), 6 Maro Itoje, 5 Nick Isiekwe, 4 Charlie Ewels, 3 Will Stuart, 2 Jamie George, 1 Ellis Genge.
Subs: 16 Luke Cowan-Dickie, 17 Joe Marler, 18 Kyle Sinckler, 19 Olli Chessum, 20 Sam Simmonds, 21 Ben Youngs, 22 George Ford, 23 Elliot Daly.
Italy – 15 Edoardo Padovani, 14 Federico Mori, 13 Juan Ignacio Brex, 12 Marco Zanon, 11 Monty Ioane, 10 Paolo Garbisi, 9 Stephen Varney, 8 Toa Halafihi, 7 Michele Lamaro (c), 6 Braam Steyn, 5 Federico Ruzza, 4 Niccolo Cannone, 3 Pietro Ceccarelli, 2 Gianmarco Lucchesi, 1 Danilo Fischetti.
Subs: 16 Epalahame Faiva, 17 Cherif Traore, 18 Tiziano Pasquali, 19 David Sisi, 20 Sebastian Negri, 21 Giovanni Pettinelli, 22 Alessandro Fusco, 23 Leonardo Marin.
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